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href='/topic/show?id=cf292341925' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=cf292341925' target=_blank style='color:#2F92EE;'>#乙肝#</a></a>，不过目前也仅9-10%的<a href='/topic/show?id=f9d08524be' target=_blank style='color:#2F92EE;'>#HBV#</a>感染者在接受24周治疗后实现。如果长时间，会不会有更高比例的治愈率？？确实<a href='/topic/show?id=cf292341925' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=cf292341925' target=_blank style='color:#2F92EE;'>#乙肝#</a></a>与<a href='/topic/show?id=d14f2092446' target=_blank style='color:#2F92EE;'>#丙肝#</a>相比，难搞多了!, objectTitle=NEJM：Bepirovirsen可实现HBV感染者长期功能性治愈, objectType=article, longId=751011, objectId=6c25e5101102, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20221207/1670400514594_2051781.png, objectUrl=/article/show_article.do?id=6c25e5101102, replyNumber=0, likeNumber=36, createdTime=2023-09-07, rootId=0, userName=侠胆医心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, 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followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=2116819, encodeId=c9012116819ad, content=这个研究对中国有现实意义，因为中国合并<a href='/topic/show?id=3d745346316' target=_blank style='color:#2F92EE;'>#慢性乙型肝炎#</a>的人很多。合并的<a href='/topic/show?id=f9d08524be' target=_blank style='color:#2F92EE;'>#HBV#</a>再激活率为2.0%，这个比例也不小了，值得重视。不过分析发现，<a href='/topic/show?id=820e3228e1b' target=_blank style='color:#2F92EE;'>#利妥昔单抗#</a>(RTX)、<a href='/topic/show?id=60ba9e805ae' target=_blank style='color:#2F92EE;'>#阿巴西普#</a>以及<a href='/topic/show?id=35791023eaf' target=_blank style='color:#2F92EE;'>#JAK抑制剂#</a>、白介素-6(IL-6)和肿瘤坏死因子-α(TNF-α)抑制剂的<a href='/topic/show?id=fdd01053199b' target=_blank style='color:#2F92EE;'>#HBV再激活率#</a>为9.0%，6.0% ，1.0%，0.0%，0.0%。总体而言，JAK抑制剂是安全的，当然<a href='/topic/show?id=e0d7546812c' target=_blank style='color:#2F92EE;'>#托珠单抗#</a>等更安全, objectTitle=Immun Inflamm Dis：生物制剂或JAK抑制剂治疗类风湿性关节炎后HBsAg -/ HBcAb+患者乙型肝炎再激活的风险, objectType=article, longId=761107, 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objectUrl=/article/show_article.do?id=e010e3066291, replyNumber=0, likeNumber=79, createdTime=2023-01-25, rootId=0, userName=klivis, userId=e87531, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=e010e3066291, moduleTitle=Front Immunol：HBV感染肝癌患者接受PD-1抑制剂联合治疗时HBV DNA和乙肝表面抗原水平与肿瘤疗效、肝功能和免疫学指标的相关性, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=e010e3066291)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1836709, encodeId=77c21836e099c, content=<a href='/topic/show?id=f9d08524be' target=_blank style='color:#2F92EE;'>#HBV#</a>, objectTitle=ARD：乙型肝炎感染缓解患者的平均糖皮质激素剂量及HBV再激活和肝炎发作的风险, objectType=article, longId=293698, objectId=5b3f29369804, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/article/show_article.do?id=5b3f29369804, replyNumber=0, likeNumber=53, createdTime=2022-09-01, rootId=0, userName=klivis, userId=e87531, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=5b3f29369804, moduleTitle=ARD：乙型肝炎感染缓解患者的平均糖皮质激素剂量及HBV再激活和肝炎发作的风险, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=5b3f29369804)], followStatus=false, userIsMember=false, type=1, lengthMark=0)] 梅斯话题小助手

2020-05-29

梅斯管理员 (审核中...)

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#HBV# #临床管理# #代谢功能障碍#

专家论坛｜施军平：合并代谢功能障碍的慢性HBV感染者的临床管理

2024-04-03发表于陕西省

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#肝癌# #HBV# #生物学标志物# #miR-4461#

【AASLD2023速递】miR-4461可作为预测HBV相关肝癌的生物学标志物

2024-04-03发表于陕西省

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#聚乙二醇干扰素α# #HBV# #HBsAg#

【期刊导读】首个荟萃分析：聚乙二醇干扰素α治疗慢性HBV感染患者获得HBsAg清除的预测因素

2024-03-27发表于陕西省

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#HBV# #抗病毒治疗#

【会议撷萃】窦晓光教授：治疗目标决定HBV感染者抗病毒治疗时机

2024-03-26发表于陕西省

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#慢乙肝# #HBsAg# #HBV#

【临床治愈集结号】初治HBeAg阴性慢乙肝患者HBsAg仍阳性时多次停药致病情反复，经多轮PEG IFNα治疗终获临床治愈

2024-03-22发表于上海

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#脂肪性肝病# #HBV# #MAFLD#

述评｜李婕：慢性HBV感染与代谢相关脂肪性肝病：已知与未知

2024-03-22发表于上海

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#慢乙肝# #肝癌# #HBV#

【APASL2024速递】77.3%存在HBV整合——长期核苷治疗的HBV相关肝癌患者

2024-03-21发表于上海

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#HBV# #危重孕产妇#

临床研究｜41例慢性HBV感染危重孕产妇的临床特征分析

2024-03-15发表于上海

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#非酒精性脂肪性肝病# #HBV# #NAFLD# #肝纤维化# #肝脏炎症#

【期刊导读】合并NAFLD的慢性HBV感染者更容易存在显著肝脏炎症和进展期肝纤维化

2024-03-10发表于上海

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#HBsAg# #乙肝疫苗# #HBV#

【全球听说】崔富强教授团队：2019年全球5岁以下儿童HBsAg流行率为0.9%

2024-03-05发表于上海

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#HBV# #慢乙肝# #ALT#

【期刊导读】吴超教授团队：ALT正常但HBV DNA可检测到的慢乙肝患者存在较大的疾病进展风险

2024-03-02发表于上海

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#肝细胞癌# #HBV#

Gut：中国医学科学院赵宏/焦宇辰/蔡建强等合作发现HBV整合重塑基因组结构促进肝细胞癌

2024-02-25发表于上海

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#HBV# #乙肝病毒# #母婴传播#

Nat Med：黄荷凤/王福生/张文宏点评！侯金林/刘志华团队发表实施多层级干预阻断乙肝病毒母婴传播真实世界研究成果

2024-02-01发表于陕西省

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#多发性骨髓瘤# #HBV#

2024-01-27发表于上海

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#乙型肝炎# #HBV# #AAV载体# #分泌信号肽#

Gut：复旦大学王勇翔/袁正宏发现抑制乙肝表面抗原分泌的新策略

2023-12-03发表于上海

(审核中...)

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#bepirovirsen#可实现#HBV感染者#长期#功能性治愈##乙肝#，不过目前也仅9-10%的#HBV#感染者在接受24周治疗后实现。如果长时间，会不会有更高比例的治愈率？？确实 #乙肝#与#丙肝#相比，难搞多了!

NEJM：Bepirovirsen可实现HBV感染者长期功能性治愈

2023-09-07发表于上海

klivis (审核中...)

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#HBV#

Front Immunol：中国南方河源市隐匿性乙型肝炎病毒感染献血者中发现的高频显著HBV突变

2022-08-15

showtest (审核中...)

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全文收起这个研究对中国有现实意义，因为中国合并#慢性乙型肝炎#的人很多。合并的#HBV#再激活率为2.0%，这个比例也不小了，值得重视。不过分析发现，#利妥昔单抗#(RTX)、#阿巴西普#以及#JAK抑制剂#、白介素-6(IL-6)和肿瘤坏死因子-α(TNF-α)抑制剂的#HBV再激活率#为9.0%，6.0% ，1.0%，0.0%，0.0%。总体而言，JAK抑制剂是安全的，当然#托珠单抗#等更安全

Immun Inflamm Dis：生物制剂或JAK抑制剂治疗类风湿性关节炎后HBsAg -/ HBcAb+患者乙型肝炎再激活的风险

2023-02-28发表于上海

klivis (审核中...)

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#HBV#

Front Immunol：HBV感染肝癌患者接受PD-1抑制剂联合治疗时HBV DNA和乙肝表面抗原水平与肿瘤疗效、肝功能和免疫学指标的相关性

2023-01-25

klivis (审核中...)

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#HBV#

ARD：乙型肝炎感染缓解患者的平均糖皮质激素剂量及HBV再激活和肝炎发作的风险

2022-09-01

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