糖尿病肾病-话题@MedSci

#糖尿病肾病#

41篇内容 | 4993人围观

关注话题

话题活跃用户

#插入话题

插入图片

最新最热

[GetTopicListResponse(id=1220756, encodeId=53e61220e5609, content=<a href='/topic/show?id=03d91019032d' target=_blank style='color:#2F92EE;'>#骨钙素#</a>与<a href='/topic/show?id=4f77e665253' target=_blank style='color:#2F92EE;'>#糖尿病#</a>和<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>, objectTitle=Diabetes Care：骨钙素与糖尿病和糖尿病肾病的风险, objectType=article, longId=294917, objectId=6cd529491e15, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/2022130/1643507684610_1739456.jpg, objectUrl=/article/show_article.do?id=6cd529491e15, replyNumber=0, likeNumber=204, createdTime=2022-05-18, rootId=0, userName=赛华佗, userId=7a3710, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=6cd529491e15, moduleTitle=Diabetes Care：骨钙素与糖尿病和糖尿病肾病的风险, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=6cd529491e15)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1206734, encodeId=2af71206e3488, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>学习了, objectTitle=糖尿病肾病, objectType=topic, longId=76760, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20201119/1605779409137_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=133, createdTime=2022-03-28, rootId=0, userName=ms3000000874455998, userId=162b5598790, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1206191, encodeId=af761206191f2, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>, objectTitle=糖尿病肾病临床分期, objectType=scale, longId=2722, objectId=2722, topicUrl=null, isHasObj=0, objectCover=https://static.medsci.cn/public-image/ms-image/c4014af0-a4f3-11ec-a1b8-6123b3ff61ea_企业微信截图_16472234662720.png, objectUrl=https://m.medsci.cn//scale/show.do?id=87662e2284, replyNumber=0, likeNumber=129, createdTime=2022-03-26, rootId=0, userName=医者仁者, userId=7a3710, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=2722, moduleTitle=糖尿病肾病临床分期, moduleType=scale, hrefUrl=https://m.medsci.cn/scale/show.do?id=87662e2284)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1205921, encodeId=8ac31205921c5, content=<a href='/topic/show?id=4f77e665253' target=_blank style='color:#2F92EE;'>#糖尿病#</a>的<a href='/topic/show?id=3c531016e571' target=_blank style='color:#2F92EE;'>#骨折#</a>风险，应该需要加强关注了，除掉<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>，视网膜病变等外，心肌病变，骨折都很重要, objectTitle=2型糖尿病患者10年内髋骨骨折风险评估, objectType=scale, longId=2235, objectId=2235, topicUrl=null, isHasObj=0, objectCover=https://static.medsci.cn/public-image/ms-image/c4014af0-a4f3-11ec-a1b8-6123b3ff61ea_企业微信截图_16472234662720.png, objectUrl=https://m.medsci.cn//scale/show.do?id=b97e223562, replyNumber=0, likeNumber=180, createdTime=2022-03-25, rootId=0, userName=医者仁者, userId=7a3710, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=2235, moduleTitle=2型糖尿病患者10年内髋骨骨折风险评估, moduleType=scale, hrefUrl=https://m.medsci.cn/scale/show.do?id=b97e223562)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1199829, encodeId=719f119982904, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>控制血糖，预防并发症。, objectTitle=糖尿病肾病, objectType=topic, longId=76760, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20201119/1605779409137_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=120, createdTime=2022-03-06, rootId=0, userName=moyanju2796, userId=cbcd5675699, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1194436, encodeId=ac061194436df, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>根据世界糖尿病协会统计，糖尿病发病率逐年递增，到2035年约有5.92亿糖尿病患者。糖尿病肾病是糖尿病的重要并发症之一，发病机制复杂，其中肾小管上皮细胞受损和纤维化是导致肾脏功能下降的主要原因。本研究首次揭示了肿瘤坏死因子α诱导蛋白8样分子 1(TIPE1)在高糖刺激下表达增加并导致肾小管上皮细胞线粒体功能受损，进而促进糖尿病肾病的进展。本研究发现了TIPE1可以与PHB2相结合，通过蛋白酶体途径促进PHB2的泛素化降解，下调PHB2表达下降，从而导致线粒体自噬活性下降、功能受损，促进糖尿病肾病进展。同时，本研究利用临床标本证实了TIPE1表达与肾脏纤维化和肾功能具有明显的相关性，可能为今后糖尿病肾病的治疗提供了新的靶点。, objectTitle=糖尿病肾病, objectType=topic, longId=76760, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20201119/1605779409137_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=115, createdTime=2022-02-17, rootId=0, userName=yangchou, userId=88b489038, projectId=1, avatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJlfgys76DEiaNtbYo2re3ibjrUPTRibEXRyFwAB4aAGiave842S0FQDf0wAoaH226NiaSoPPDzhndsf1g/132, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=1), GetTopicListResponse(id=1194389, encodeId=4fbc119438948, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>, objectTitle=Redox biology：马春红/杨向东教授团队在糖尿病肾病与自噬调控领域取得新进展, objectType=article, longId=299019, objectId=9e2e29901950, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/2022217/1645064332712_5635644.png, objectUrl=/article/show_article.do?id=9e2e29901950, replyNumber=0, likeNumber=150, createdTime=2022-02-17, rootId=0, userName=医者仁者, userId=7a3710, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=9e2e29901950, moduleTitle=Redox biology：马春红/杨向东教授团队在糖尿病肾病与自噬调控领域取得新进展, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=9e2e29901950)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1055416, encodeId=931510554169d, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>延长寿命减少并发症, objectTitle=糖尿病肾病, objectType=topic, longId=76760, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20201119/1605779409137_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=144, createdTime=2021-09-27, rootId=0, userName=ms5000002033807255, userId=24185619352, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1003219, encodeId=1c381003219e9, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>积极预防糖尿病肾病的发生很重要, objectTitle=糖尿病肾病, objectType=topic, longId=76760, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20201119/1605779409137_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=177, createdTime=2021-07-28, rootId=0, userName=smart Ren, userId=b3545492917, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1001103, encodeId=a7c31001103ba, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>控制血糖，保护肾脏, objectTitle=糖尿病肾病, objectType=topic, longId=76760, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20201119/1605779409137_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=146, createdTime=2021-07-20, rootId=0, userName=醫着仁心, userId=be9c5237904, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=972373, encodeId=73959e237365, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>科学早期预防, objectTitle=糖尿病肾病, objectType=topic, longId=76760, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20201119/1605779409137_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=173, createdTime=2021-06-10, rootId=0, userName=smart Ren, userId=b3545492917, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=969557, encodeId=67da96955e9c, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>如果因糖尿病肾病达到了终末期肾病，可以考虑胰肾联合移植, objectTitle=糖尿病肾病, objectType=topic, longId=76760, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20201119/1605779409137_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=145, createdTime=2021-05-29, rootId=0, userName=ms2000001193205877, userId=69015509833, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=964864, encodeId=75e7964864e4, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>预防最重要!, objectTitle=糖尿病肾病, objectType=topic, longId=76760, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20201119/1605779409137_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=141, createdTime=2021-05-12, rootId=0, userName=chenny, userId=a8312408082, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=960872, encodeId=0c399608e25b, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>治疗还是没有太大办法, objectTitle=糖尿病肾病, objectType=topic, longId=76760, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20201119/1605779409137_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=142, createdTime=2021-04-27, rootId=0, userName=bigsteam, userId=3cfa1712572, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=952541, encodeId=8fb2952541fd, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>发病率逐年增高, objectTitle=糖尿病肾病, objectType=topic, longId=76760, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20201119/1605779409137_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=128, createdTime=2021-03-31, rootId=0, userName=chuntianzihan, userId=bcaf1405665, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=949800, encodeId=d8ec9498005c, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>治未病之病。, objectTitle=糖尿病肾病, objectType=topic, longId=76760, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20201119/1605779409137_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=160, createdTime=2021-03-20, rootId=0, userName=言西早, userId=13511650672, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=925143, encodeId=f38592514357, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>预防为主。, objectTitle=糖尿病肾病, objectType=topic, longId=76760, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20201119/1605779409137_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=167, createdTime=2021-02-17, rootId=0, userName=zhouqu_8, userId=fa4716, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=897112, encodeId=ca7989e112f7, content=<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>研究进展，2019年的, objectTitle=2019年梅斯医盘点：糖尿病肾病研究进展, objectType=article, longId=186186, objectId=b40d18618608, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/webeditor/uploadfile/202001/20200113090728740.jpeg, objectUrl=/article/show_article.do?id=b40d18618608, replyNumber=0, likeNumber=208, createdTime=2020-11-05, rootId=0, userName=lovetcm, userId=7a3710, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=b40d18618608, moduleTitle=2019年梅斯医盘点：糖尿病肾病研究进展, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=b40d18618608)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=897111, encodeId=1be889e11180, content=<a href='/topic/show?id=3d6a323398d' target=_blank style='color:#2F92EE;'>#别嘌呤醇#</a>不能改善<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>功能, objectTitle=NEJM：别嘌呤醇不能改善糖尿病肾病患者肾功能, objectType=article, longId=196466, objectId=73ff196466bc, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/2020625/1593049796305_2051781.jpg, objectUrl=/article/show_article.do?id=73ff196466bc, replyNumber=0, likeNumber=238, createdTime=2020-11-05, rootId=0, userName=lovetcm, userId=7a3710, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=73ff196466bc, moduleTitle=NEJM：别嘌呤醇不能改善糖尿病肾病患者肾功能, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=73ff196466bc)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=897110, encodeId=085d89e110bf, content=APSN临床实践<a href='/topic/show?id=c14d5638971' target=_blank style='color:#2F92EE;'>#指南#</a>：<a href='/topic/show?id=b081e6760b8' target=_blank style='color:#2F92EE;'>#糖尿病肾病#</a>, objectTitle=2020 APSN临床实践指南：糖尿病肾病 , objectType=guider, longId=12662, objectId=c812c1c00200235c, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/guideline/show_article.do?id=c812c1c00200235c, replyNumber=0, likeNumber=224, createdTime=2020-11-05, rootId=0, userName=lovetcm, userId=7a3710, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=c812c1c00200235c, moduleTitle=2020 APSN临床实践指南：糖尿病肾病 , moduleType=guider, hrefUrl=https://www.medsci.cn/guideline/show_article.do?id=c812c1c00200235c)], followStatus=false, userIsMember=false, type=1, lengthMark=0)] 梅斯话题小助手

糖尿病并发症不再，不仅是糖肾

2020-05-29

赛华佗 (审核中...)

前往app查看评论内容

#骨钙素#与#糖尿病#和#糖尿病肾病#

Diabetes Care：骨钙素与糖尿病和糖尿病肾病的风险

2022-05-18

ms3000000874455998 (审核中...)

前往app查看评论内容

#糖尿病肾病#学习了

2022-03-28

医者仁者 (审核中...)

前往app查看评论内容

#糖尿病肾病#

糖尿病肾病临床分期

2022-03-26

医者仁者 (审核中...)

前往app查看评论内容

#糖尿病#的#骨折#风险，应该需要加强关注了，除掉#糖尿病肾病#，视网膜病变等外，心肌病变，骨折都很重要

2型糖尿病患者10年内髋骨骨折风险评估

2022-03-25

moyanju2796 (审核中...)

前往app查看评论内容

#糖尿病肾病#控制血糖，预防并发症。

2022-03-06

yangchou (审核中...)

前往app查看评论内容

全文收起 #糖尿病肾病#根据世界糖尿病协会统计，糖尿病发病率逐年递增，到2035年约有5.92亿糖尿病患者。糖尿病肾病是糖尿病的重要并发症之一，发病机制复杂，其中肾小管上皮细胞受损和纤维化是导致肾脏功能下降的主要原因。本研究首次揭示了肿瘤坏死因子α诱导蛋白8样分子 1(TIPE1)在高糖刺激下表达增加并导致肾小管上皮细胞线粒体功能受损，进而促进糖尿病肾病的进展。本研究发现了TIPE1可以与PHB2相结合，通过蛋白酶体途径促进PHB2的泛素化降解，下调PHB2表达下降，从而导致线粒体自噬活性下降、功能受损，促进糖尿病肾病进展。同时，本研究利用临床标本证实了TIPE1表达与肾脏纤维化和肾功能具有明显的相关性，可能为今后糖尿病肾病的治疗提供了新的靶点。

2022-02-17

医者仁者 (审核中...)

前往app查看评论内容

#糖尿病肾病#

Redox biology：马春红/杨向东教授团队在糖尿病肾病与自噬调控领域取得新进展

2022-02-17

ms5000002033807255 (审核中...)

前往app查看评论内容

#糖尿病肾病#延长寿命减少并发症

2021-09-27

smart Ren (审核中...)

前往app查看评论内容

#糖尿病肾病#积极预防糖尿病肾病的发生很重要

2021-07-28

醫着仁心 (审核中...)

前往app查看评论内容

#糖尿病肾病#控制血糖，保护肾脏

2021-07-20

smart Ren (审核中...)

前往app查看评论内容

#糖尿病肾病#科学早期预防

2021-06-10

ms2000001193205877 (审核中...)

前往app查看评论内容

#糖尿病肾病#如果因糖尿病肾病达到了终末期肾病，可以考虑胰肾联合移植

2021-05-29

chenny (审核中...)

前往app查看评论内容

#糖尿病肾病#预防最重要!

2021-05-12

bigsteam (审核中...)

前往app查看评论内容

#糖尿病肾病#治疗还是没有太大办法

2021-04-27

chuntianzihan (审核中...)

前往app查看评论内容

#糖尿病肾病#发病率逐年增高

2021-03-31

言西早 (审核中...)

前往app查看评论内容

#糖尿病肾病#治未病之病。

2021-03-20

zhouqu_8 (审核中...)

前往app查看评论内容

#糖尿病肾病#预防为主。

2021-02-17

lovetcm (审核中...)

前往app查看评论内容

#糖尿病肾病#研究进展，2019年的

2019年梅斯医盘点：糖尿病肾病研究进展

2020-11-05

lovetcm (审核中...)

前往app查看评论内容

#别嘌呤醇#不能改善#糖尿病肾病#功能

NEJM：别嘌呤醇不能改善糖尿病肾病患者肾功能

2020-11-05

lovetcm (审核中...)

前往app查看评论内容

APSN临床实践#指南#：#糖尿病肾病#

2020 APSN临床实践指南：糖尿病肾病

2020-11-05

科室
- - 订阅+
  - 更多科室
工具
服务