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#CRISPR#

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GetTopicListResponse(id=2172036, encodeId=84be21e2036e8, content=<a href='/topic/show?id=755d5211a0' target=_blank style='color:#2F92EE;'>#CRISPR#</a> <a href='/topic/show?id=58b18265cf' target=_blank style='color:#2F92EE;'>#gRNA#</a> <a href='/topic/show?id=1dc2108050ff' target=_blank style='color:#2F92EE;'>#FLSHclust#</a>, objectTitle=Science：利用FLSHclust新算法发现188种新的CRISPR/Cas系统, objectType=article, longId=802450, objectId=5b298024501f, topicUrl=null, isHasObj=0, objectCover=https://msimg.bioon.com/bioon-com/20231126/1700971729822_2185383.png, objectUrl=/article/show_article.do?id=5b298024501f, replyNumber=0, likeNumber=63, createdTime=2023-11-30, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=0, avatar=, status=0, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=null, followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2169302, encodeId=3cd32169302f2, content=<a href='/topic/show?id=755d5211a0' target=_blank style='color:#2F92EE;'>#CRISPR#</a> <a href='/topic/show?id=0a7ee13177e' target=_blank style='color:#2F92EE;'>#癌症免疫治疗#</a> <a href='/topic/show?id=8e2310e51879' target=_blank style='color:#2F92EE;'>#肿瘤T细胞#</a> <a href='/topic/show?id=a27310e519ea' target=_blank style='color:#2F92EE;'>#CTLs#</a>, objectTitle=迟洪波团队最新Nature：利用体内单细胞CRISPR筛选，绘制肿瘤T细胞命运调控网络, objectType=article, longId=801305, objectId=48cd80130552, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/nurse-writing-on-a-clipboard-in-the-hospital-PZ3P5XL.jpg, objectUrl=/article/show_article.do?id=48cd80130552, replyNumber=0, likeNumber=95, createdTime=2023-11-18, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=48cd80130552, moduleTitle=迟洪波团队最新Nature：利用体内单细胞CRISPR筛选，绘制肿瘤T细胞命运调控网络, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=48cd80130552)], followStatus=false, 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CRISPR

2020-05-29

梅斯管理员 (审核中...)

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#肿瘤# #CRISPR# #TNF信号#

Nature：揭示肿瘤进化新机制：体内单细胞CRISPR筛选解码TNF信号

2024-07-20发表于上海

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#癌症# #基因检测# #CRISPR# #CoHIT#

IVD前沿丨one-pot超灵敏CRISPR系统，临床癌症诊断可能取得大进展

2024-07-07发表于上海

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#CRISPR# #化疗耐药# #遗传驱动#

Nat Commun：东北大学费腾等团队合作通过CRISPR筛选揭示癌症化疗耐药性的遗传驱动策略

2024-07-07发表于上海

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#急性白血病# #CRISPR# #PI3Kγ#

Nature：罗擎宇等人发现靶向非经典PI3Kγ信号和天然免疫治疗急性白血病

2024-05-14发表于上海

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#CRISPR# #基因编辑#

CRISPR技术进化史 | 24年 Cell 综述

2024-03-08发表于上海

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#CRISPR# #RNA编辑#

Nature：RNA编辑：有望超越CRISPR的未来疗法

2024-02-24发表于上海

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#T细胞# #CRISPR# #碱基编辑#

2023-12-20发表于上海

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#CRISPR# #gRNA# #FLSHclust#

2023-11-30发表于上海

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#CRISPR# #癌症免疫治疗# #肿瘤T细胞# #CTLs#

迟洪波团队最新Nature：利用体内单细胞CRISPR筛选，绘制肿瘤T细胞命运调控网络

2023-11-18发表于上海

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全文收起 #CRISPR##基因编辑#治疗后死亡，尸检结果显示，或源于对#AAV载体#的免疫反应，如果真是发现对AAV载体的免疫反应，那反而是件好事，以后只要测试对AAV过敏的人就不再使用这个载体即可！这也算是对基因编辑的重大贡献。现在对于基因编辑治疗另一个难题在于疗效会随时间推移不断减退，但是AAV载体原则上一个人一辈子只能使用一次！！疗效减退了，怎么办？

medRxiv：一名DMD患者接受CRISPR基因编辑治疗后死亡，尸检结果显示，或源于对AAV载体的免疫反应

2023-05-21发表于上海

lifestar (审核中...)