孟德尔随机化-话题@MedSci

#孟德尔随机化#

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content=<a href='/topic/show?id=aa61954695c' target=_blank style='color:#2F92EE;'>#酒精#</a> <a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a> <a href='/topic/show?id=73af45392ca' target=_blank style='color:#2F92EE;'>#孟德尔随机化#</a> <a href='/topic/show?id=4ffa10830229' target=_blank style='color:#2F92EE;'>#中国慢性病前瞻性研究#</a>, objectTitle=一滴酒也致命！超50万中国人大样本显示，饮酒没有“安全量”！每周多喝100g，死亡风险高18%, objectType=article, longId=803992, objectId=b0698039920e, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20231207/1701912382907_5651580.png, objectUrl=/article/show_article.do?id=b0698039920e, replyNumber=0, likeNumber=137, createdTime=2023-12-07, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=b0698039920e, moduleTitle=一滴酒也致命！超50万中国人大样本显示，饮酒没有“安全量”！每周多喝100g，死亡风险高18%, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=b0698039920e)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2172247, encodeId=293021e2247c4, content=<a href='/topic/show?id=43ed1080e969' target=_blank style='color:#2F92EE;'>#UK biobank#</a>,<a href='/topic/show?id=73af45392ca' target=_blank style='color:#2F92EE;'>#孟德尔随机化#</a>. <a href='/topic/show?id=ce9d239823b' target=_blank style='color:#2F92EE;'>#二甲双胍#</a>可能通过目标 <a href='/topic/show?id=8eb910808193' target=_blank style='color:#2F92EE;'>#GPD1#</a> 和 <a href='/topic/show?id=21911080826a' target=_blank style='color:#2F92EE;'>#AMPKγ2#</a> (PRKAG2) 促进健康<a href='/topic/show?id=4c239032154' target=_blank style='color:#2F92EE;'>#衰老#</a>，其效果可能部分归因于其<a href='/topic/show?id=ead9898189d' target=_blank style='color:#2F92EE;'>#血糖#</a>特性。我们的研究结果支持对二甲双胍和<a href='/topic/show?id=74f3969028e' target=_blank style='color:#2F92EE;'>#长寿#</a>的进一步临床研究。<a href='/topic/show?id=d06e55e807f' target=_blank style='color:#2F92EE;'>#抗衰老#</a>, objectTitle=Lancet Healthy Longev：二甲双胍对表型年龄和白细胞端粒长度的影响的孟德尔随机化研究, objectType=article, longId=781753, objectId=c2bce8175362, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20230715/1689471437513_4754896.jpg, objectUrl=/article/show_article.do?id=c2bce8175362, replyNumber=0, likeNumber=169, createdTime=2023-12-01, rootId=0, userName=侠胆医心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=威斯康星, moduleDTOList=[ModuleDTO(moduleId=c2bce8175362, moduleTitle=Lancet Healthy Longev：二甲双胍对表型年龄和白细胞端粒长度的影响的孟德尔随机化研究, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=c2bce8175362)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=2172150, encodeId=64e821e2150ee, content=利用双样本<a href='/topic/show?id=73af45392ca' target=_blank style='color:#2F92EE;'>#孟德尔随机化#</a>（MR）研究<a href='/topic/show?id=b1fd816e094' target=_blank style='color:#2F92EE;'>#肠道微生物#</a>与<a href='/topic/show?id=cb65813029a' target=_blank style='color:#2F92EE;'>#肝硬化#</a>之间的潜在因果关系。 <a href='/topic/show?id=de675021419' target=_blank style='color:#2F92EE;'>#当归#</a>、<a href='/topic/show?id=5eb12311579' target=_blank style='color:#2F92EE;'>#丹参#</a>、<a href='/topic/show?id=497610533696' target=_blank style='color:#2F92EE;'>#茯苓#</a>、<a href='/topic/show?id=37fd105333e0' target=_blank style='color:#2F92EE;'>#白芍#</a>、<a href='/topic/show?id=9c2d1031961f' target=_blank style='color:#2F92EE;'>#黄芪#</a>、<a href='/topic/show?id=ec1c1055e7c6' target=_blank style='color:#2F92EE;'>#苍术#</a>为主要药用植物。植物性药物和<a href='/topic/show?id=6ebc81e3482' target=_blank style='color:#2F92EE;'>#肠道菌群#</a>靶向<a href='/topic/show?id=43eb1080e586' target=_blank style='color:#2F92EE;'>#MAPK1#</a>、VEGFA、<a href='/topic/show?id=684f16e52c8' target=_blank style='color:#2F92EE;'>#STAT3#</a>、AKT1、RELA、JUN和ESR1治疗<a href='/topic/show?id=1a942339426' target=_blank style='color:#2F92EE;'>#乙型肝炎#</a>肝硬化，它们的联合使用显示出肝硬化治疗的希望。, objectTitle=Front Cell Infect Microbiol：中医药与肠道菌群在肝硬化改善中的融合应用，数据挖掘和孟德尔随机化研究, objectType=article, longId=802986, objectId=86ab80298689, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20231130/1701312075205_5610093.jpg, objectUrl=/article/show_article.do?id=86ab80298689, replyNumber=0, likeNumber=138, createdTime=2023-11-30, rootId=0, userName=侠胆医心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=威斯康星, moduleDTOList=[ModuleDTO(moduleId=86ab80298689, moduleTitle=Front Cell Infect Microbiol：中医药与肠道菌群在肝硬化改善中的融合应用，数据挖掘和孟德尔随机化研究, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=86ab80298689)], followStatus=false, userIsMember=false, type=1, lengthMark=1), GetTopicListResponse(id=2172053, encodeId=c0ea21e2053ac, content=<a href='/topic/show?id=9c645e74223' target=_blank style='color:#2F92EE;'>#数据挖掘#</a> <a href='/topic/show?id=053d2148601' target=_blank style='color:#2F92EE;'>#中医药#</a> <a href='/topic/show?id=6ebc81e3482' target=_blank style='color:#2F92EE;'>#肠道菌群#</a> <a href='/topic/show?id=73af45392ca' target=_blank style='color:#2F92EE;'>#孟德尔随机化#</a> <a href='/topic/show?id=4ace108059d0' target=_blank style='color:#2F92EE;'>#网络分析#</a> <a href='/topic/show?id=8b0c10806024' target=_blank style='color:#2F92EE;'>#乙型肝炎肝硬化#</a>, objectTitle=Front Cell Infect Microbiol：中医药与肠道菌群在肝硬化改善中的融合应用，数据挖掘和孟德尔随机化研究, objectType=article, longId=802986, objectId=86ab80298689, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20231130/1701312075205_5610093.jpg, objectUrl=/article/show_article.do?id=86ab80298689, replyNumber=0, likeNumber=120, createdTime=2023-11-30, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=86ab80298689, moduleTitle=Front Cell Infect Microbiol：中医药与肠道菌群在肝硬化改善中的融合应用，数据挖掘和孟德尔随机化研究, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=86ab80298689)], followStatus=false, userIsMember=false, type=null, lengthMark=0)] 梅斯话题小助手

孟德尔随机化

2020-05-29

梅斯管理员 (审核中...)

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#肠道微生物群# #血液恶性肿瘤# #孟德尔随机化#

Front Cell Infect Microbiol：肠道微生物群与常见血液恶性肿瘤之间的关系——双向孟德尔随机化研究

2024-11-13发表于上海

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#肠道菌群# #孟德尔随机化# #血清代谢物#

Front Immunol：淋巴白血病的因果途径——肠道微生物群、免疫细胞和血清代谢物

2024-11-09发表于上海

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#孟德尔随机化#

发文新思路！5分钟读懂：SCI新宠儿「孟德尔随机化」

2024-11-05发表于上海

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#认知能力# #体力活动# #孟德尔随机化#

颠覆！我国学者最新：中高强度的锻炼竟会导致认知能力下降？“运动伤脑”的结论是如何得到的？

2024-11-02发表于上海

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#氧化应激# #高脂血症# #脂质代谢# #载脂蛋白B# #孟德尔随机化# #柚皮素#

Front Pharmacol：柚皮素调节氧化应激和脂质代谢：来自网络药理学、孟德尔随机化和分子对接的见解

2024-10-31发表于上海

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#氧化应激# #基因表达# #重度抑郁# #孟德尔随机化#

Translational Psychiatry：朱刚教授通过多组学和多性状研究发现与氧化应激相关的重度抑郁症的新治疗靶点

2024-10-20发表于上海

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#耳鸣# #网络药理学# #分子对接# #孟德尔随机化# #HIF1A# #小柴胡汤#

Heliyon：网络药理学和生物信息学方法探讨小柴胡汤治疗耳鸣的作用机制

2024-09-25发表于上海

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#阿尔茨海默病# #孟德尔随机化# #读写障碍#

Translational Psychiatry：读写障碍与八种痴呆症风险的因果关系

2024-09-15发表于上海

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#物质使用障碍# #转录组学# #孟德尔随机化#

JAMA Psychiatry：主要精神疾病、物质使用行为与寿命的关系研究

2024-08-02发表于上海

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