结直肠癌-话题@MedSci

#结直肠癌#

126篇内容 | 10284人围观

关注话题

话题活跃用户

#插入话题

插入图片

最新最热

[GetTopicListResponse(id=2241087, encodeId=d374224108e4d, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=b67d8244123' target=_blank style='color:#2F92EE;'>#肾上腺素#</a>, objectTitle=论文解读 | Gaoping Zhao/Zili Zhou教授团队揭示肾上腺素促进结直肠癌细胞进展和肿瘤相关巨噬细胞M2极化, objectType=article, longId=852977, objectId=3d798529e7d7, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20240703/1719979466467_5579292.png, objectUrl=/article/show_article.do?id=3d798529e7d7, replyNumber=0, likeNumber=2, createdTime=3小时前, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=陕西省, moduleDTOList=[ModuleDTO(moduleId=3d798529e7d7, moduleTitle=论文解读 | Gaoping Zhao/Zili Zhou教授团队揭示肾上腺素促进结直肠癌细胞进展和肿瘤相关巨噬细胞M2极化, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=3d798529e7d7)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2240701, encodeId=c67e2240e011c, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=be1312200102' target=_blank style='color:#2F92EE;'>#空肠弯曲杆菌#</a>, objectTitle=Cell子刊：中山大学兰平等发现空肠弯曲杆菌衍生的细胞致死膨胀毒素促进结直肠癌转移！, objectType=article, longId=853727, objectId=8619853e279f, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20241202/1733135607274_8538692.jpg, objectUrl=/article/show_article.do?id=8619853e279f, replyNumber=0, likeNumber=7, createdTime=2024-12-03, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=陕西省, moduleDTOList=[ModuleDTO(moduleId=8619853e279f, moduleTitle=Cell子刊：中山大学兰平等发现空肠弯曲杆菌衍生的细胞致死膨胀毒素促进结直肠癌转移！, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=8619853e279f)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2240600, encodeId=6ac32240600de, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=6b058150307' target=_blank style='color:#2F92EE;'>#肝转移#</a>, objectTitle=JAMA子刊：结直肠癌肝转移一线治疗，“简化方案”有望成为首选, objectType=article, longId=852462, objectId=a103852462bf, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/doctor-writing-D3K6QME.jpg, objectUrl=/article/show_article.do?id=a103852462bf, replyNumber=0, likeNumber=7, createdTime=2024-12-03, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=陕西省, moduleDTOList=[ModuleDTO(moduleId=a103852462bf, moduleTitle=JAMA子刊：结直肠癌肝转移一线治疗，“简化方案”有望成为首选, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=a103852462bf)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2240501, encodeId=7d2f2240501bd, content=<a href='/topic/show?id=19d412195921' target=_blank style='color:#2F92EE;'>#马普替林#</a>通过靶向E3泛素连接酶（SPOP）抑制PD-L1表达，从而发挥抗肿瘤作用（图4D-F）。此外，研究者通过体内实验发现，马普替林与抗细胞毒性T淋巴细胞相关抗原4（<a href='/topic/show?id=4440540855' target=_blank style='color:#2F92EE;'>#CTLA-4#</a>）药物具有协同作用，能够发挥更好抗肿瘤效果（图4G-H）。本研究揭示了马普替林在抗肿瘤方面的潜在应用价值，为<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a>和<a href='/topic/show?id=384b8220449' target=_blank style='color:#2F92EE;'>#肺癌#</a>的临床治疗提供了新的策略。<a href='/topic/show?id=9efb80281aa' target=_blank style='color:#2F92EE;'>#老药新用#</a><a href='/topic/show?id=6c6b5559ea5' target=_blank style='color:#2F92EE;'>#抗精神病药物#</a>, objectTitle=Adv Sci：四环类抗抑郁药物马普替林靶向E3泛素连接酶SPOP发挥抗肿瘤作用, objectType=article, longId=853692, objectId=720a853692b2, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/images/20241101/8d5771f423b84325b7e8fed3b5d8d20a-Rxpba1RaOY8H.jpg, objectUrl=/article/show_article.do?id=720a853692b2, replyNumber=0, likeNumber=6, createdTime=2024-12-03, rootId=0, userName=侠胆医心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=威斯康星, moduleDTOList=[ModuleDTO(moduleId=720a853692b2, moduleTitle=Adv Sci：四环类抗抑郁药物马普替林靶向E3泛素连接酶SPOP发挥抗肿瘤作用, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=720a853692b2)], followStatus=false, userIsMember=false, type=1, lengthMark=1), GetTopicListResponse(id=2239821, encodeId=59a7223982136, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=2756103612e5' target=_blank style='color:#2F92EE;'>#新辅助免疫治疗#</a> <a href='/topic/show?id=733811136610' target=_blank style='color:#2F92EE;'>#MSI-H #</a>, objectTitle=大咖谈 | 2024年MSI-H 早期CRC的新辅助免疫治疗探索, objectType=article, longId=852700, objectId=f5ca852e0082, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/2022223/1645580399978_5552845.jpg, objectUrl=/article/show_article.do?id=f5ca852e0082, replyNumber=0, likeNumber=9, createdTime=2024-11-28, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=f5ca852e0082, moduleTitle=大咖谈 | 2024年MSI-H 早期CRC的新辅助免疫治疗探索, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=f5ca852e0082)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2239818, encodeId=6d9e22398187c, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=56b0194220e' target=_blank style='color:#2F92EE;'>#一线治疗#</a>, objectTitle=NEJM：2年无进展生存率72%！一线双重免疫疗法大幅改善结直肠癌疗效, objectType=article, longId=852459, objectId=a88385245936, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20241128/1732759665632_8538692.jpg, objectUrl=/article/show_article.do?id=a88385245936, replyNumber=0, likeNumber=9, createdTime=2024-11-28, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=a88385245936, moduleTitle=NEJM：2年无进展生存率72%！一线双重免疫疗法大幅改善结直肠癌疗效, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=a88385245936)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2239835, encodeId=829b223983561, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=358118e4513' target=_blank style='color:#2F92EE;'>#wnt通路#</a>, objectTitle=Adv Sci：复旦大学王鲁等团队合作研究揭示Wnt通路转录调控抑制结直肠癌肿瘤生长并增强化疗敏感性, objectType=article, longId=853047, objectId=13fc85304e73, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20241128/1732784852293_8538692.png, objectUrl=/article/show_article.do?id=13fc85304e73, replyNumber=0, likeNumber=5, createdTime=2024-11-28, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=13fc85304e73, moduleTitle=Adv Sci：复旦大学王鲁等团队合作研究揭示Wnt通路转录调控抑制结直肠癌肿瘤生长并增强化疗敏感性, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=13fc85304e73)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2239665, encodeId=91e6223966522, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a><a href='/topic/show?id=daf52906537' target=_blank style='color:#2F92EE;'>#免疫治疗#</a>结直肠癌80%是MSS型。, objectTitle=大咖谈 | 2024年MSS 结直肠癌免疫治疗进展及探索, objectType=article, longId=852699, objectId=bdd885269949, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20241127/1732676703140_8538692.jpg, objectUrl=/article/show_article.do?id=bdd885269949, replyNumber=0, likeNumber=7, createdTime=2024-11-28, rootId=0, userName=liuyf0307, userId=43812963388, projectId=1, avatar=https://img.medsci.cn/202410/7be9c3cb6d1a4807b2b2f87e7832b635-1qQDmzDzZuNh.jpg, status=1, hasArticle=1, attachment=null, ipAttribution=山东省, moduleDTOList=[ModuleDTO(moduleId=bdd885269949, moduleTitle=大咖谈 | 2024年MSS 结直肠癌免疫治疗进展及探索, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=bdd885269949)], followStatus=false, userIsMember=true, type=1, lengthMark=0), GetTopicListResponse(id=2239642, encodeId=300e223964229, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=daf52906537' target=_blank style='color:#2F92EE;'>#免疫治疗#</a>, objectTitle=大咖谈 | 2024年MSS 结直肠癌免疫治疗进展及探索, objectType=article, longId=852699, objectId=bdd885269949, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20241127/1732676703140_8538692.jpg, objectUrl=/article/show_article.do?id=bdd885269949, replyNumber=0, likeNumber=16, createdTime=2024-11-27, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=bdd885269949, moduleTitle=大咖谈 | 2024年MSS 结直肠癌免疫治疗进展及探索, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=bdd885269949)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2238696, encodeId=2da7223869620, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=654712161e9c' target=_blank style='color:#2F92EE;'>#无丝氨酸/甘氨酸饮食#</a>, objectTitle=Cell子刊：四川大学马学磊等报告了无丝氨酸/甘氨酸饮食治疗实体肿瘤的治疗潜力！, objectType=article, longId=851726, objectId=47a2851e2633, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20241122/1732254479398_8538692.png, objectUrl=/article/show_article.do?id=47a2851e2633, replyNumber=1, likeNumber=11, createdTime=2024-11-23, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=陕西省, moduleDTOList=[ModuleDTO(moduleId=47a2851e2633, moduleTitle=Cell子刊：四川大学马学磊等报告了无丝氨酸/甘氨酸饮食治疗实体肿瘤的治疗潜力！, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=47a2851e2633)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2238554, encodeId=790b223855478, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=fe2b142e95c' target=_blank style='color:#2F92EE;'>#PIK3CA#</a>, objectTitle=晚期结直肠癌应关注PIK3CA多重打击突变及其伴随突变，潜在获益于PI3K抑制剂及联合治疗, objectType=article, longId=851616, objectId=2259851616e9, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/2022328/1648453045714_5552845.jpg, objectUrl=/article/show_article.do?id=2259851616e9, replyNumber=0, likeNumber=13, createdTime=2024-11-22, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=陕西省, moduleDTOList=[ModuleDTO(moduleId=2259851616e9, moduleTitle=晚期结直肠癌应关注PIK3CA多重打击突变及其伴随突变，潜在获益于PI3K抑制剂及联合治疗, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=2259851616e9)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2238135, encodeId=a7e5223813507, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=2e6e6e0315d' target=_blank style='color:#2F92EE;'>#炎症性肠病#</a> <a href='/topic/show?id=4ec01113833' target=_blank style='color:#2F92EE;'>#LXR#</a>, objectTitle=Nature：两全其美！激活LXR蛋白在促进肠道再生的同时抑制结直肠癌产生, objectType=article, longId=851891, objectId=112a851891cb, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/bioon-com/20241121/1732144392656_2185383.png, objectUrl=/article/show_article.do?id=112a851891cb, replyNumber=0, likeNumber=18, createdTime=2024-11-21, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=0, avatar=, status=0, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=null, followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2237136, encodeId=5535223e136f3, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=f30312132483' target=_blank style='color:#2F92EE;'>#PD-1/PD-L1阻断#</a>, objectTitle=Mol Cancer：梁婧/潘景轩团队合作揭示提高PD-1/PD-L1阻断对结直肠癌患者疗效的新策略, objectType=article, longId=851299, objectId=0b25851299f5, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20240925/1727233846342_8538692.png, objectUrl=/article/show_article.do?id=0b25851299f5, replyNumber=0, likeNumber=18, createdTime=2024-11-15, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=0b25851299f5, moduleTitle=Mol Cancer：梁婧/潘景轩团队合作揭示提高PD-1/PD-L1阻断对结直肠癌患者疗效的新策略, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=0b25851299f5)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2236014, encodeId=adca22360142f, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=3cebe7184f2' target=_blank style='color:#2F92EE;'>#红肉#</a>, objectTitle=猪牛羊肉居然会促癌！每多吃一口，都可能增加患癌风险, objectType=article, longId=850505, objectId=9df8850505ff, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20221109/1668024453437_4754896.jpeg, objectUrl=/article/show_article.do?id=9df8850505ff, replyNumber=0, likeNumber=23, createdTime=2024-11-09, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=9df8850505ff, moduleTitle=猪牛羊肉居然会促癌！每多吃一口，都可能增加患癌风险, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=9df8850505ff)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2234985, encodeId=6afd223498594, content=<a href='/topic/show?id=00cf120952e0' target=_blank style='color:#2F92EE;'>#氧化苦参碱#</a>联合<a href='/topic/show?id=b9091031981b' target=_blank style='color:#2F92EE;'>#黄芪甲苷#</a>调节免疫：实现低毒高效抗<a href='/topic/show?id=33771982175' target=_blank style='color:#2F92EE;'>#三阴性乳腺癌#</a>。不过，这个也会存疑。事实上临床上有一种中药注射剂<a href='/topic/show?id=18791209538a' target=_blank style='color:#2F92EE;'>#岩舒#</a>主要成分就是<a href='/topic/show?id=69388e02586' target=_blank style='color:#2F92EE;'>#苦参#</a>、<a href='/topic/show?id=e88210545470' target=_blank style='color:#2F92EE;'>#白土苓#</a>，在临床上应用约30年，但是并没有看到特别好的效果。另外从<a href='/topic/show?id=c01b2138812' target=_blank style='color:#2F92EE;'>#中医#</a>上看，苦参属于大寒苦燥类药物，对于热性肿瘤可能效果较好，如<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a>。但是对于寒性为主的肿瘤，可能适得其反，如<a href='/topic/show?id=251e10183059' target=_blank style='color:#2F92EE;'>#骨肉瘤#</a>。三阴性乳腺癌具体寒热尚不清楚，不过HR+HER2-乳腺癌一般是寒性乳腺癌，而HER2+HR-乳腺癌则属于热性<a href='/topic/show?id=73c423e2572' target=_blank style='color:#2F92EE;'>#乳腺癌#</a>，也许这一类苦参可能有一定的作用。黄芪甲苷倒具有一定的免疫促进作用，对于各种<a href='/topic/show?id=aa0582e6946' target=_blank style='color:#2F92EE;'>#肿瘤#</a>都应该是有效的。 , objectTitle=氧化苦参碱联合黄芪甲苷调节免疫：实现低毒高效抗三阴性乳腺癌, objectType=article, longId=815947, objectId=d9e081594e45, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20221109/1668024114319_4754896.jpeg, objectUrl=/article/show_article.do?id=d9e081594e45, replyNumber=0, likeNumber=83, createdTime=2024-11-04, rootId=0, userName=侠胆医心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=威斯康星, moduleDTOList=[ModuleDTO(moduleId=d9e081594e45, moduleTitle=氧化苦参碱联合黄芪甲苷调节免疫：实现低毒高效抗三阴性乳腺癌, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=d9e081594e45)], followStatus=false, userIsMember=false, type=1, lengthMark=1), GetTopicListResponse(id=2234578, encodeId=318c22345e8a1, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a>, objectTitle=聚焦结直肠癌：为临床医生整理的优质资料集, objectType=article, longId=849531, objectId=7be28495314d, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20241101/1730446955003_8538692.png, objectUrl=/article/show_article.do?id=7be28495314d, replyNumber=0, likeNumber=11, createdTime=2024-11-01, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=7be28495314d, moduleTitle=聚焦结直肠癌：为临床医生整理的优质资料集, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=7be28495314d)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2234482, encodeId=cef122344820f, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=daf52906537' target=_blank style='color:#2F92EE;'>#免疫治疗#</a>, objectTitle=读书报告 | 微卫星稳定转移性结直肠的免疫治疗反应受转移部位影响, objectType=article, longId=849374, objectId=1d638493e429, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20240904/1725427927213_8538692.jpg, objectUrl=/article/show_article.do?id=1d638493e429, replyNumber=0, likeNumber=47, createdTime=2024-11-01, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=1d638493e429, moduleTitle=读书报告 | 微卫星稳定转移性结直肠的免疫治疗反应受转移部位影响, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=1d638493e429)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2234293, encodeId=1c0c223429375, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=0b0546822fd' target=_blank style='color:#2F92EE;'>#射频消融#</a> <a href='/topic/show?id=bc745030edf' target=_blank style='color:#2F92EE;'>#影像组学#</a> <a href='/topic/show?id=10a191163af' target=_blank style='color:#2F92EE;'>#计算机断层扫描#</a>, objectTitle=【论著】| 基于CT的影像组学诺模图预测结直肠癌肺转移射频消融后的局部肿瘤进展, objectType=article, longId=849286, objectId=c76084928694, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20230720/1689790189324_5579292.jpg, objectUrl=/article/show_article.do?id=c76084928694, replyNumber=0, likeNumber=28, createdTime=2024-10-31, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=c76084928694, moduleTitle=【论著】| 基于CT的影像组学诺模图预测结直肠癌肺转移射频消融后的局部肿瘤进展, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=c76084928694)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2234292, encodeId=d3142234292b9, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=1a5a58e00ad' target=_blank style='color:#2F92EE;'>#新辅助治疗#</a> <a href='/topic/show?id=8f7b12082800' target=_blank style='color:#2F92EE;'>#阳性淋巴结比率#</a>, objectTitle=【论著】| 探索阳性淋巴结比率在ypⅢ期结直肠癌患者中的预后价值及预测模型的建立, objectType=article, longId=849283, objectId=267984928386, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/202401028/1730092206609_8538692.png, objectUrl=/article/show_article.do?id=267984928386, replyNumber=0, likeNumber=28, createdTime=2024-10-31, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=267984928386, moduleTitle=【论著】| 探索阳性淋巴结比率在ypⅢ期结直肠癌患者中的预后价值及预测模型的建立, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=267984928386)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2234268, encodeId=a43a2234268f3, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=680f3699146' target=_blank style='color:#2F92EE;'>#厚朴#</a> <a href='/topic/show?id=382710e36f0' target=_blank style='color:#2F92EE;'>#LC-MS#</a> <a href='/topic/show?id=8d82e952353' target=_blank style='color:#2F92EE;'>#网络药理学#</a> <a href='/topic/show?id=8a1f3159524' target=_blank style='color:#2F92EE;'>#分子对接#</a>, objectTitle=J Ethnopharmacol：厚朴对结直肠癌的作用及机制：多组分-多靶点研究, objectType=article, longId=849255, objectId=b0d98492555f, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20231103/1698995635796_8096338.jpg, objectUrl=/article/show_article.do?id=b0d98492555f, replyNumber=0, likeNumber=37, createdTime=2024-10-31, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=b0d98492555f, moduleTitle=J Ethnopharmacol：厚朴对结直肠癌的作用及机制：多组分-多靶点研究, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=b0d98492555f)], followStatus=false, userIsMember=false, type=null, lengthMark=0)] 梅斯话题小助手

让结直肠癌远离人类！

2020-05-29

梅斯管理员 (审核中...)

前往app查看评论内容

#结直肠癌# #肾上腺素#

论文解读 | Gaoping Zhao/Zili Zhou教授团队揭示肾上腺素促进结直肠癌细胞进展和肿瘤相关巨噬细胞M2极化

3小时前发表于陕西省

梅斯管理员 (审核中...)

前往app查看评论内容

#结直肠癌# #空肠弯曲杆菌#

Cell子刊：中山大学兰平等发现空肠弯曲杆菌衍生的细胞致死膨胀毒素促进结直肠癌转移！

2024-12-03发表于陕西省

梅斯管理员 (审核中...)

前往app查看评论内容

#结直肠癌# #肝转移#

JAMA子刊：结直肠癌肝转移一线治疗，“简化方案”有望成为首选

2024-12-03发表于陕西省

侠胆医心 (审核中...)

前往app查看评论内容

全文收起 #马普替林#通过靶向E3泛素连接酶（SPOP）抑制PD-L1表达，从而发挥抗肿瘤作用（图4D-F）。此外，研究者通过体内实验发现，马普替林与抗细胞毒性T淋巴细胞相关抗原4（#CTLA-4#）药物具有协同作用，能够发挥更好抗肿瘤效果（图4G-H）。本研究揭示了马普替林在抗肿瘤方面的潜在应用价值，为#结直肠癌#和#肺癌#的临床治疗提供了新的策略。#老药新用##抗精神病药物#

Adv Sci：四环类抗抑郁药物马普替林靶向E3泛素连接酶SPOP发挥抗肿瘤作用

2024-12-03发表于威斯康星

梅斯管理员 (审核中...)

前往app查看评论内容

#结直肠癌# #新辅助免疫治疗# #MSI-H #

大咖谈 | 2024年MSI-H 早期CRC的新辅助免疫治疗探索

2024-11-28

梅斯管理员 (审核中...)

前往app查看评论内容

#结直肠癌# #一线治疗#

NEJM：2年无进展生存率72%！一线双重免疫疗法大幅改善结直肠癌疗效

2024-11-28

梅斯管理员 (审核中...)

前往app查看评论内容

#结直肠癌# #wnt通路#

Adv Sci：复旦大学王鲁等团队合作研究揭示Wnt通路转录调控抑制结直肠癌肿瘤生长并增强化疗敏感性

2024-11-28

(审核中...)

前往app查看评论内容

#结直肠癌##免疫治疗#结直肠癌80%是MSS型。

大咖谈 | 2024年MSS 结直肠癌免疫治疗进展及探索

2024-11-28发表于山东省

梅斯管理员 (审核中...)

前往app查看评论内容

#结直肠癌# #免疫治疗#

大咖谈 | 2024年MSS 结直肠癌免疫治疗进展及探索

2024-11-27

梅斯管理员 (审核中...)