HFpEF-话题@MedSci

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moduleDTOList=[ModuleDTO(moduleId=c88181110681, moduleTitle=天津医科大学陈雄文教授团队揭示钙信号紊乱是促进HFpEF发生发展的重要因素, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=c88181110681)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2090562, encodeId=773420905623c, content=FXI（<a href='/topic/show?id=723a104854bd' target=_blank style='color:#2F92EE;'>#凝血因子 XI#</a>）是内源性<a href='/topic/show?id=997b31316c5' target=_blank style='color:#2F92EE;'>#凝血因子#</a>，其活化后促进凝血因子IX的活化，进而促进凝血。其缺失的患者不仅<a href='/topic/show?id=fa10e93597f' target=_blank style='color:#2F92EE;'>#缺血性卒中#</a>和主要<a href='/topic/show?id=38c451e4317' target=_blank style='color:#2F92EE;'>#心血管事件#</a>风险降低，且出血风险也有所降低。FXI具有保护<a href='/topic/show?id=028e8e805e' target=_blank style='color:#2F92EE;'>#HFpEF#</a>中心脏舒张功能损伤的作用，其信号机制独立于传统发现的凝血途径。一方面，这项研究仅初步证实了FXI具有这一作用，另一方面，进一步证实了BMP7-SMAD1/5通路可能能成为HFpEF的治疗的关键<a href='/topic/show?id=07a69996557' target=_blank style='color:#2F92EE;'>#靶点#</a>。<a 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attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=396a1e744489, moduleTitle=JACC-Heart Failure：营养不良与HFpEF患者心血管风险增加相关, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=396a1e744489)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1313201, encodeId=24201313201b8, content=<a href='/topic/show?id=028e8e805e' target=_blank style='color:#2F92EE;'>#HFpEF#</a>, objectTitle=Circulation：HFpEF定义不统一对临床的影响, objectType=article, longId=177320, objectId=140d1e73202a, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/article/show_article.do?id=140d1e73202a, replyNumber=0, likeNumber=97, createdTime=2019-08-10, rootId=0, userName=bettycmoon, userId=ffd5416, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=140d1e73202a, moduleTitle=Circulation：HFpEF定义不统一对临床的影响, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=140d1e73202a)], followStatus=false, userIsMember=false, type=1, lengthMark=0)] 梅斯话题小助手

HFpEF

2020-05-29

小小医者 (审核中...)

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降低#尿酸#可能改善伴有#高尿酸血症#的#射血分数保留心衰#患者预后。#痛风#与#HFpEF#有关吗？

JAHA：降低尿酸可能改善伴有高尿酸血症的射血分数保留心衰患者预后

2022-09-27

梅斯管理员 (审核中...)

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#药物治疗# #HFpEF#

射血分数保留的心衰患者治疗取得了哪些进展？| 干货总结

2024-11-02发表于上海

梅斯管理员 (审核中...)

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#心力衰竭# #HFpEF#

Ageing Res Rev 四川大学基础医学强基计划班本科生张哲维同学发表系统综述：衰老视角下的射血分数保留型心力衰竭

2024-10-27发表于上海

梅斯管理员 (审核中...)

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#心力衰竭# #HFpEF#

研究人员开发新的评分系统，以更好地筛查和治疗 HFpEF 心力衰竭患者

2024-08-03发表于上海

梅斯管理员 (审核中...)

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#HFpEF# #三尖瓣反流#

J Am Coll Cardiol：HFpEF与三尖瓣反流（TR）的病理、风险与治疗管理

2024-07-09发表于上海

梅斯管理员 (审核中...)

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#心肌细胞# #小鼠# #HFpEF# #Ca2+#

天津医科大学陈雄文教授团队揭示钙信号紊乱是促进HFpEF发生发展的重要因素

2024-01-30发表于上海

小小医者 (审核中...)

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全文收起 FXI（#凝血因子 XI#）是内源性#凝血因子#，其活化后促进凝血因子IX的活化，进而促进凝血。其缺失的患者不仅#缺血性卒中#和主要#心血管事件#风险降低，且出血风险也有所降低。FXI具有保护#HFpEF#中心脏舒张功能损伤的作用，其信号机制独立于传统发现的凝血途径。一方面，这项研究仅初步证实了FXI具有这一作用，另一方面，进一步证实了BMP7-SMAD1/5通路可能能成为HFpEF的治疗的关键#靶点#。#射血分数保留心衰#

Science：心肝互作在射血分数保留心衰中的作用机制

2022-09-27

bettycmoon (审核中...)

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#HFpEF#

ESC 2022：沙库巴曲/缬沙坦对HFmrEF和HFpEF患者认知功能无影响（PERSPECTIVE研究）

2022-08-29

bettycmoon (审核中...)

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#HFpEF#

射血分数保留的心力衰竭 (HFpEF) 的肺动脉高压病理生理学

2022-05-20

bettycmoon (审核中...)

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#HFpEF#

PAH与PH-HFpEF如何区别

2022-05-20

bettycmoon (审核中...)

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#HFpEF#

JAHA：抑郁症状、心脏结构和功能与HFpEF和HFrEF风险的关系

2021-11-25

bettycmoon (审核中...)

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#HFpEF#

Circulation：保留射血分数的心衰（HFpEF）患者运动诱发肺充血的能量基础

2021-11-25

bettycmoon (审核中...)

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#HFpEF#

EHJ：“宝藏药”沙库巴曲-缬沙坦作为治疗HFpEF合并难治性高血压患者的疗效

2021-08-23

bettycmoon (审核中...)

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#HFpEF#

Eur Heart J：沙库巴曲缬沙坦可降低HFpEF患者的明显顽固性高血压

2021-08-20

bettycmoon (审核中...)

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#HFpEF#

J Am Coll Cardiol：螺内酯相关的肾功能恶化对HFpEF患者预后的影响

2021-03-08

bettycmoon (审核中...)

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#HFpEF#

李新立：射血分数保留心力衰竭（HFpEF）合并高血压的治疗策略

2021-01-10

bettycmoon (审核中...)

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#HFpEF#

OCC 2020丨周京敏：HFpEF新认识

2020-06-04

bettycmoon (审核中...)

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#HFpEF#

JACC：年轻HFpEF患者更常见于肥胖男性，且猝死率高

2019-08-13

bettycmoon (审核中...)

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#HFpEF#

JACC-Heart Failure：营养不良与HFpEF患者心血管风险增加相关

2019-08-13

bettycmoon (审核中...)

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#HFpEF#

Circulation：HFpEF定义不统一对临床的影响

2019-08-10

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